IL-10 Protein (AA 19-178) (His tag)
-
- Target See all IL-10 (IL10) Proteins
- IL-10 (IL10) (Interleukin 10 (IL10))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 19-178
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL-10 protein is labelled with His tag.
- Purpose
- Recombinant Human IL10 protein with N-terminal 6xHis tag
- Specificity
- 6xHis tag IL10 (Ser19-Asn178)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product IL10 Protein
-
Interleukin 10 (IL10) (AA 19-178) protein
IL10 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 10 (IL10) (AA 19-178) (Active) proteinIL10 Origin: Human Host: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Interleukin 10 (IL10) protein (His-Avi Tag)IL10 Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Interleukin 10 (IL10) protein (His-Avi Tag,Biotin)IL10 Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Interleukin 10 (IL10) (Active) proteinIL10 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 10 (IL10) (AA 22-178) protein (His tag)IL10 Origin: Hamster Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interleukin 10 (IL10) (AA 74-178) protein (GST tag)IL10 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 10 (IL10) (AA 1-178) protein (GST tag)IL10 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 10 (IL10) proteinIL10 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
-
- Target
- IL-10 (IL10) (Interleukin 10 (IL10))
- Alternative Name
- IL10 (IL10 Products)
- Synonyms
- CSIF Protein, GVHDS Protein, IL-10 Protein, IL10A Protein, TGIF Protein, Il-10 Protein, IL10X Protein, interleukin 10 Protein, IL10 Protein, Il10 Protein
- Background
- The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, May 2020]
- Molecular Weight
- predicted molecular mass of 19.5 kDa after removal of the signal peptide. The apparent molecular mass of His-IL10 is 15-25 kDa due to glycosylation.
- UniProt
- P22301
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
-
