CCL28 Protein

Catalog No. ABIN7455692

Product Details

Target: CCL28 (Chemokine (C-C Motif) Ligand 28 (CCL28))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purpose: Recombinant Human C-C Motif Chemokine 28 is produced by our E.coli expression system and the target gene encoding Ser20-Tyr127 is expressed.

Characteristics: Extracellular Domain Protein

Purification: Affinity purification

Purity: Greater than 95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: CCL28 (Chemokine (C-C Motif) Ligand 28 (CCL28))

Alternative Name: CCL28 (CCL28 Products)

Synonyms: Scya28 Protein, CCL28 Protein, ccl28 Protein, nrpb Protein, enc-1 Protein, pig10 Protein, Encr-3 Protein, klhl35 Protein, Xencr-3 Protein, tp53i10 Protein, LOC100303767 Protein, CCK1 Protein, MEC Protein, SCYA28 Protein, C-C motif chemokine ligand 28 Protein, ectodermal-neural cortex 1 (with BTB domain) Protein, C-C motif chemokine 28 Protein, chemokine (C-C motif) ligand 28 Protein, Ccl28 Protein, CCL28 Protein, ccl28 Protein, enc1 Protein, LOC100303767 Protein

Background: Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel chemokine that shares the most homology with CCL27/CTACK. CCL28 shows chemotactic activity for resting CD4, CD8 T-cells and eosinophils. It Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. CCR10 (GPR2 orphan receptor) is also the receptor for CCL27/CTACK. CCL28 is preferentially expressed by epithelial cells of diverse tissues, with highest expression level in normal and pathological colon. It is also expressed in normal and asthmatic lung tissues. Human and mouse CCL28 shares 83 % sequence identity in their mature regions.

Molecular Weight: 12.49 KDa

UniProt: Q9NRJ3