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CCL5 Protein

CCL5 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7455688
  • Target See all CCL5 Proteins
    CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
    Protein Type
    Recombinant
    Origin
    • 17
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Source
    • 26
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purpose
    Recombinant Human C-C Motif Chemokine 5 is produced by our E.coli expression system and the target gene encoding Ser24-Ser91 is expressed.
    Characteristics
    Extracellular Domain Protein
    Purification
    Affinity purification
    Purity
    Greater than 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product CCL5 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
    Alternative Name
    CCL5 (CCL5 Products)
    Synonyms
    Rantes Protein, Scya5 Protein, D17S136E Protein, RANTES Protein, SCYA5 Protein, SIS-delta Protein, SISd Protein, TCP228 Protein, eoCP Protein, MuRantes Protein, C-C motif chemokine 5-like Protein, C-C motif chemokine ligand 5 Protein, chemokine (C-C motif) ligand 5 Protein, LOC100230935 Protein, CCL5 Protein, Ccl5 Protein
    Background
    Human Chemokine (C-C Motif) Ligand 5 (CCL5) plays an active role in recruiting leukocytes into inflammatory sites. CCL5 is secreted by many cell types at inflammatory sites and it exerts a wide range of activities through the receptors CCR1, CCR3, CCR4, and CCR5. N-Terminal truncated CCL5/RANTES, Met-RANTES, and amino-oxypentane (AOP)-RANTES exhibit antagonist or partial agonist functions on their receptors. CCL5/RANTES attracts different subtypes of leukocytes into inflamed tissue and intervenes in a wide range of allergic and autoimmune diseases.
    Molecular Weight
    7.8 KDa
    UniProt
    P13501
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
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