CCL8 Protein (His tag)
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- Target See all CCL8 Proteins
- CCL8 (Chemokine (C-C Motif) Ligand 8 (CCL8))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CCL8 protein is labelled with His tag.
- Purpose
- Recombinant Human C-C Motif Chemokine 8 is produced by our Mammalian expression system and the target gene encoding Gln24-Pro99 is expressed with a 6His tag at the C-terminus.
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- Greater than 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product CCL8 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 1 mM EDTA, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CCL8 (Chemokine (C-C Motif) Ligand 8 (CCL8))
- Alternative Name
- CCL8 (CCL8 Products)
- Synonyms
- HC14 Protein, MCP-2 Protein, MCP2 Protein, SCYA10 Protein, SCYA8 Protein, 1810063B20Rik Protein, AB023418 Protein, Mcp2 Protein, Scya8 Protein, C-C motif chemokine ligand 8 Protein, chemokine (C-C motif) ligand 8 Protein, C-C motif chemokine 8 Protein, monocyte chemoattractant protein-2 precursor Protein, CCL8 Protein, Ccl8 Protein, LOC101119572 Protein, MCP-2 Protein
- Background
- Human Chemokine (C-C Motif) Ligand 8 (CCL8) is produced by human MG63 osteosarcoma cells. CCL8 shares 62 % and 58 % amino acid sequence identity with MCP-1 and MCP-3, respectively. All three MCP proteins are monocyte chemoattractants. CCL8 is chemotactic for and activates many different immune cells, including mast cells, eosinophils and basophils, which are implicated in allergic response, and monocytes, T cells, and NK cells that are involved in the inflammatory response. CCL8 elicits its effects by binding to several different cell surface receptors including CCR1, CCR2B and CCR5.
- Molecular Weight
- 9.95 KDa
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