FGF12 Protein
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- Target See all FGF12 Proteins
- FGF12 (Fibroblast Growth Factor 12 (FGF12))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purpose
- Recombinant Human Fibroblast Growth Factor 12 is produced by our E.coli expression system and the target gene encoding Met1-Thr181 is expressed.
- Characteristics
- Extracellular Domain Protein
- Purification
- Affinity purification
- Purity
- Greater than 95 % as determined by reducing SDS-PAGE.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, 5 mM EDTA, pH 7.5.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- FGF12 (Fibroblast Growth Factor 12 (FGF12))
- Alternative Name
- FGF-12 (FGF12 Products)
- Synonyms
- FHF1 Protein, FHF-1 Protein, MGC84150 Protein, FGF12 Protein, fgf12 Protein, zgc:153104 Protein, fhf1 Protein, fgf12b Protein, DKFZp459P139 Protein, FGF12B Protein, AV114868 Protein, FGF-12 Protein, Fhf1 Protein, Fhf1b Protein, fibroblast growth factor 12 Protein, fibroblast growth factor 12 S homeolog Protein, fibroblast growth factor 12a Protein, FGF12 Protein, fgf12.S Protein, fgf12a Protein, fgf12 Protein, Fgf12 Protein
- Background
- Fibroblast Growth Factor 12 (FGF-12) is a member of the fibroblast growth factor (FGF) family. FGF-12 is probably involved in nervous system development and function. FGF-12 lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfectedinto mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.
- Molecular Weight
- 20.45 KDa
- UniProt
- P61328-2
- Pathways
- Negative Regulation of Transporter Activity
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