MYDGF Protein (His tag)
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- Target See all MYDGF (D17Wsu104e) Proteins
- MYDGF (D17Wsu104e) (DNA segment, Chr 17, Wayne State University 104, expressed (D17Wsu104e))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This MYDGF protein is labelled with His tag.
- Purpose
- Recombinant Human Myeloid-derived Growth Factor is produced by our E.coli expression system and the target gene encoding Ser33-Leu173 is expressed with a 6His tag at the N-terminus.
- Characteristics
- Extracellular Domain Protein
- Purification
- Affinity purification
- Purity
- Greater than 95 % as determined by reducing SDS-PAGE.
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DNA segment, Chr 17, Wayne State University 104, expressed (D17Wsu104e) (AA 32-173) protein (His tag)
D17Wsu104e Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
DNA segment, Chr 17, Wayne State University 104, expressed (D17Wsu104e) (AA 25-166) protein (His tag)D17Wsu104e Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 4 mM HCl.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- MYDGF (D17Wsu104e) (DNA segment, Chr 17, Wayne State University 104, expressed (D17Wsu104e))
- Alternative Name
- MYDGF (D17Wsu104e Products)
- Synonyms
- EUROIMAGE1875335 Protein, IL25 Protein, IL27 Protein, IL27w Protein, R33729_1 Protein, SF20 Protein, Il25 Protein, Ly6elg Protein, myeloid derived growth factor Protein, MYDGF Protein, Mydgf Protein
- Background
- Myeloid-derived growth factor (MYDGF) is a secreted protein which belongs to the UPF0556 family. MYDGF was strongly expressed in spleen, prostate and lung, and weakly expressed in the left ventricle and liver. Bone marrow-derived monocyte and paracrine-acting protein promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). MYDGF stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. It inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway. MYDGF is involved in endothelial cell proliferation and angiogenesis. It may serve as a prototypical example for the development of protein-based therapies for ischemic tissue repair.
- Molecular Weight
- 18 KDa
- UniProt
- Q969H8
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