BTN3A1 Protein (AA 1-218) (His tag)
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- Target See all BTN3A1 Proteins
- BTN3A1 (Butyrophilin, Subfamily 3, Member A1 (BTN3A1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-218
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Origin
- Cynomolgus
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This BTN3A1 protein is labelled with His tag.
- Purpose
- Recombinant Cynomolgus BTN3A1 protein with C-terminal 6xHis tag
- Specificity
- BTN3A1 (Gln1-Ser218) 6xHis tag
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product BTN3A1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- BTN3A1 (Butyrophilin, Subfamily 3, Member A1 (BTN3A1))
- Alternative Name
- BTN3A1 (BTN3A1 Products)
- Synonyms
- BT3.1 Protein, BTF5 Protein, CD277 Protein, BTN3A1 Protein, butyrophilin subfamily 3 member A1 Protein, BTN3A1 Protein, LOC100447925 Protein
- Background
- Butyrophilin subfamily 3 member A1 (BTN3A1) is also known as CD277 and BTF5, which belongs to the immunoglobulin superfamily and contains one B30.2/SPRY domain and two Ig-like V-type (immunoglobulin-like) domains. BTN3A1 plays a role in T-cell activation and in the adaptive immune response. Also, BTN3A1 regulates the proliferation of activated T-cells and the release of cytokines and IFNG by activated T-cells. Furthermore, BTN3A1 mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.
- Molecular Weight
- predicted molecular mass of 24.3 kDa after removal of the signal peptide. The apparent molecular mass of cBTN3A1-His is 25-35 kDa due to glycosylation.
- UniProt
- A0A330KVC6
- Pathways
- Activated T Cell Proliferation
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