Amphiregulin Protein (AREG) (AA 20-187) (Fc Tag)
-
- Target See all Amphiregulin (AREG) Proteins
- Amphiregulin (AREG)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 20-187
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Amphiregulin protein is labelled with Fc Tag.
- Purpose
- Recombinant human AREG protein with C-terminal human Fc tag
- Specificity
- AREG (Ser20-Lys187) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product AREG Protein
-
Amphiregulin (AREG) (Active) protein
AREG Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Amphiregulin (AREG) (AA 101-187) protein (Fc Tag)AREG Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Amphiregulin (AREG) (AA 100-248) protein (Fc Tag)AREG Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Amphiregulin (AREG) (AA 101-198) protein (His tag)AREG Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Amphiregulin (AREG) (AA 1-252) protein (GST tag)AREG Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Amphiregulin (AREG) (AA 20-129) protein (GST tag)AREG Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Amphiregulin (AREG) (AA 101-198) protein (His-IF2DI Tag)AREG Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
-
- Target
- Amphiregulin (AREG)
- Alternative Name
- AREG (AREG Products)
- Synonyms
- AR Protein, CRDGF Protein, SDGF Protein, Sdgf Protein, AREG Protein, AREGB Protein, AREG/SDGF Protein, amphiregulin Protein, AREG Protein, Areg Protein
- Background
- The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. [provided by RefSeq, Apr 2014]
- Molecular Weight
- predicted molecular mass of 44.9 kDa after removal of the signal peptide. The apparent molecular mass of AREG-hFc is 53-70 kDa due to glycosylation.
- UniProt
- P15514
- Pathways
- RTK Signaling, EGFR Signaling Pathway
-
