F2RL1 Protein (AA 37-71) (Fc Tag)

Catalog No. ABIN7491171

Product Details

Target: F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))

Protein Type: Recombinant

Protein Characteristics: AA 37-71

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This F2RL1 protein is labelled with Fc Tag.

Purpose: Recombinant human F2RL1 protein with C-terminal human Fc tag

Specificity: F2RL1 (Ser37-Gly71) hFc (Glu99-Ala330)

Characteristics: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))

Alternative Name: F2RL1 (F2RL1 Products)

Synonyms: par2 Protein, GPR11 Protein, PAR2 Protein, Gpcr11 Protein, PAR-2 Protein, Par2 Protein, Par-2 Protein, Proteinase-activated receptor 2 Protein, F2R like trypsin receptor 1 Protein, coagulation factor II (thrombin) receptor-like 1 Protein, par2 Protein, F2RL1 Protein, F2rl1 Protein

Background: This gene encodes a member of the G-protein coupled receptor 1 family of proteins. The encoded cell surface receptor is activated through proteolytic cleavage of its extracellular amino terminus, resulting in a new amino terminus that acts as a tethered ligand that binds to an extracellular loop domain. Activation of the receptor has been shown to stimulate vascular smooth muscle relaxation, dilate blood vessels, increase blood flow, and lower blood pressure. This protein is also important in the inflammatory response, as well as innate and adaptive immunity. [provided by RefSeq, Jun 2016]

Molecular Weight: predicted molecular mass of 29.7 kDa after removal of the signal peptide. The apparent molecular mass of F2RL1-hFc is 33-53 kDa due to glycosylation.

UniProt: P55085

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome