CCR6 Protein (AA 1-47) (mFc Tag)
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- Target See all CCR6 Proteins
- CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-47
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CCR6 protein is labelled with mFc Tag.
- Purpose
- Recombinant human CCR6 protein with C-terminal mouse Fc tag
- Specificity
- CCR6 (Met1-Leu47) mFc (Pro99-Lys330)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product CCR6 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))
- Alternative Name
- CCR6 (CCR6 Products)
- Synonyms
- BN-1 Protein, C-C CKR-6 Protein, CC-CKR-6 Protein, CCR-6 Protein, CD196 Protein, CKR-L3 Protein, CKRL3 Protein, CMKBR6 Protein, DCR2 Protein, DRY6 Protein, GPR29 Protein, GPRCY4 Protein, STRL22 Protein, Cmkbr6 Protein, KY411 Protein, C-C motif chemokine receptor 6 Protein, chemokine (C-C motif) receptor 6 Protein, CCR6 Protein, Ccr6 Protein
- Background
- This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
- Molecular Weight
- predicted molecular mass of 31.7 kDa after removal of the signal peptide. The apparent molecular mass of CCR6-mFc is 35-55 kDa due to glycosylation.
- UniProt
- P51684
- Pathways
- cAMP Metabolic Process
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