TGFBR1 Protein (AA 34-126) (Fc Tag)
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- Target See all TGFBR1 Proteins
- TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 34-126
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TGFBR1 protein is labelled with Fc Tag.
- Purpose
- Recombinant human TGFBR1 protein with C-terminal Human Fc tag
- Specificity
- TGFBR1 (Leu34-Leu126) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product TGFBR1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))
- Alternative Name
- TGFBR1 (TGFBR1 Products)
- Synonyms
- AAT5 Protein, ACVRLK4 Protein, ALK-5 Protein, ALK5 Protein, LDS1A Protein, LDS2A Protein, MSSE Protein, SKR4 Protein, TGFR-1 Protein, aat5 Protein, acvrlk4 Protein, alk-5 Protein, alk5 Protein, lds1a Protein, lds2a Protein, skr4 Protein, tgfr-1 Protein, TGFBR1 Protein, x-trr1 Protein, AU017191 Protein, Alk-5 Protein, TbetaR-I Protein, TbetaRI Protein, Alk5 Protein, Skr4 Protein, Tgfr-1 Protein, tbetaR-I Protein, tgfbr1 Protein, zgc:123263 Protein, transforming growth factor beta receptor 1 Protein, transforming growth factor beta receptor I Protein, transforming growth factor beta receptor I S homeolog Protein, transforming growth factor, beta receptor I Protein, transforming growth factor, beta receptor 1 Protein, transforming growth factor, beta receptor 1 a Protein, TGFBR1 Protein, tgfbr1 Protein, tgfbr1.S Protein, Tgfbr1 Protein, tgfbr1a Protein
- Background
- The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- predicted molecular mass of 36.3 kDa after removal of the signal peptide.The apparent molecular mass of TGFBR1-hFc is 35-40 kDa due to glycosylation.
- UniProt
- P36897
- Pathways
- Growth Factor Binding
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