Transferrin Receptor Protein (AA 89-760) (His tag)
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- Target See all Transferrin Receptor (TFRC) Proteins
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 89-760
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Transferrin Receptor protein is labelled with His tag.
- Purpose
- Recombinant human TFRC protein with N-terminal 6xHis tag
- Specificity
- 6xHis tag TFRC (Cys89-Phe760)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product TFRC Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
- Alternative Name
- TFRC (TFRC Products)
- Synonyms
- Trfr Protein, LOC100219280 Protein, tfr Protein, cd71 Protein, tfr1 Protein, trfr Protein, CD71 Protein, T9 Protein, TFR Protein, TFR1 Protein, TR Protein, TRFR Protein, p90 Protein, 2610028K12Rik Protein, AI195355 Protein, AI426448 Protein, AU015758 Protein, E430033M20Rik Protein, Mtvr-1 Protein, Mtvr1 Protein, transferrin receptor Protein, TFRC Protein, Tfrc Protein, tfrc Protein
- Background
- This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]
- Molecular Weight
- predicted molecular mass of 76 kDa after removal of the signal peptide. The apparent molecular mass of His-TFRC is 70-100 kDa due to glycosylation.
- UniProt
- P02786
- Pathways
- Transition Metal Ion Homeostasis
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