TNFRSF12A Protein (AA 28-78) (Fc Tag)
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- Target See all TNFRSF12A Proteins
- TNFRSF12A (Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 28-78
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TNFRSF12A protein is labelled with Fc Tag.
- Purpose
- Recombinant mouse TweakR protein with C-terminal human Fc tag
- Specificity
- Mouse TweakR (Glu28-Leu78) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product TNFRSF12A Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- TNFRSF12A (Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A))
- Alternative Name
- TweakR (TNFRSF12A Products)
- Synonyms
- CD266 Protein, FN14 Protein, TWEAKR Protein, AI255180 Protein, C87282 Protein, Fn14 Protein, HPIP Protein, TWEAK-R Protein, TweakR Protein, TNF receptor superfamily member 12A Protein, tumor necrosis factor receptor superfamily, member 12a Protein, TNFRSF12A Protein, Tnfrsf12a Protein
- Background
- Receptor for TNFSF12/TWEAK (By similarity). Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.[UniProtKB/Swiss-Prot Function]
- Molecular Weight
- predicted molecular mass of 31.4 kDa after removal of the signal peptide. The apparent molecular mass of mTweakR-hFc is 25-35 kDa due to glycosylation.
- UniProt
- Q9CR75
- Pathways
- Apoptosis, Regulation of Cell Size
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