QSOX1 Protein (AA 36-708) (His tag)

Catalog No. ABIN7491030

Product Details

Target: QSOX1 (Quiescin Q6 Sulfhydryl Oxidase 1 (QSOX1))

Protein Type: Recombinant

Protein Characteristics: AA 36-708

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This QSOX1 protein is labelled with His tag.

Purpose: Recombinant mouse QSOX1 protein with C-terminal 6xHis tag

Specificity: Mouse QSOX1 (Ser36-His708) 6xHis tag

Characteristics: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Purity: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: QSOX1 (Quiescin Q6 Sulfhydryl Oxidase 1 (QSOX1))

Alternative Name: QSOX1 (QSOX1 Products)

Synonyms: qscn6l1 Protein, Qscn6 Protein, Qsox Protein, Sox-2 Protein, rSOx Protein, Q6 Protein, QSCN6 Protein, 1300003H02Rik Protein, QSOX Protein, SOx Protein, GEC-3 Protein, GEC3 Protein, SOX3 Protein, ATQSOX1 Protein, QSO2 Protein, T15D22.7 Protein, T15D22_7 Protein, quiescin-sulfhydryl oxidase 1 Protein, quiescin sulfhydryl oxidase 1 Protein, quiescin sulfhydryl oxidase 1 L homeolog Protein, quiescin Q6 sulfhydryl oxidase 1 Protein, quiescin-sulfhydryl oxidase 1 Protein, QSOX1 Protein, qsox1 Protein, qsox1.L Protein, Qsox1 Protein

Background: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide (PubMed:26819240). Plays a role in disulfide bond formation in a variety of extracellular proteins (PubMed:26819240). In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration (PubMed:26819240).[UniProtKB/Swiss-Prot Function]

Molecular Weight: predicted molecular mass of 75.5 kDa after removal of the signal peptide. The apparent molecular mass of mQSOX1-His is 70-100 kDa due to glycosylation.

UniProt: Q8BND5

Pathways: Cell RedoxHomeostasis