Ectodysplasin A Protein (EDA) (Fc Tag)
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- Target See all Ectodysplasin A (EDA) Proteins
- Ectodysplasin A (EDA)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Ectodysplasin A protein is labelled with Fc Tag.
- Purpose
- Recombinant Human EDA Protein with N-terminal human Fc tag
- Specificity
- HFc (Glu99-Ala330) EDA (Ser160-Ser391)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- Ectodysplasin A (EDA)
- Alternative Name
- EDA (EDA Products)
- Synonyms
- ECTD1 Protein, ED1 Protein, ED1-A1 Protein, ED1-A2 Protein, EDA-A1 Protein, EDA-A2 Protein, EDA1 Protein, EDA2 Protein, HED Protein, HED1 Protein, ODT1 Protein, STHAGX1 Protein, XHED Protein, XLHED Protein, si:ch73-223d24.5 Protein, Ed1 Protein, Eda-A1 Protein, Eda-A2 Protein, Ta Protein, tabby Protein, RGD1563178 Protein, ectodysplasin A Protein, ectodysplasin-A Protein, EDA Protein, eda Protein, Eda Protein
- Background
- The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Molecular Weight
- predicted molecular mass of 50.3 kDa after removal of the signal peptide.The apparent molecular mass of hFc-EDA is 55-70 kDa due to glycosylation.
- UniProt
- Q92838
- Pathways
- Tube Formation
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