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Ectodysplasin A Protein (EDA) (Fc Tag)

EDA Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7490962
  • Target See all Ectodysplasin A (EDA) Proteins
    Ectodysplasin A (EDA)
    Protein Type
    Recombinant
    Origin
    • 6
    • 4
    • 1
    Human
    Source
    • 4
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Ectodysplasin A protein is labelled with Fc Tag.
    Purpose
    Recombinant Human EDA Protein with N-terminal human Fc tag
    Specificity
    HFc (Glu99-Ala330) EDA (Ser160-Ser391)
    Characteristics
    Extracellular Domain Protein
    Purification
    Purified from cell culture supernatant by affinity chromatography
    Purity
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    Ectodysplasin A (EDA)
    Alternative Name
    EDA (EDA Products)
    Synonyms
    ECTD1 Protein, ED1 Protein, ED1-A1 Protein, ED1-A2 Protein, EDA-A1 Protein, EDA-A2 Protein, EDA1 Protein, EDA2 Protein, HED Protein, HED1 Protein, ODT1 Protein, STHAGX1 Protein, XHED Protein, XLHED Protein, si:ch73-223d24.5 Protein, Ed1 Protein, Eda-A1 Protein, Eda-A2 Protein, Ta Protein, tabby Protein, RGD1563178 Protein, ectodysplasin A Protein, ectodysplasin-A Protein, EDA Protein, eda Protein, Eda Protein
    Background
    The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
    Molecular Weight
    predicted molecular mass of 50.3 kDa after removal of the signal peptide.The apparent molecular mass of hFc-EDA is 55-70 kDa due to glycosylation.
    UniProt
    Q92838
    Pathways
    Tube Formation
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