Prolactin Receptor Protein (PRLR) (AA 25-234) (Fc Tag)
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- Target See all Prolactin Receptor (PRLR) Proteins
- Prolactin Receptor (PRLR)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 25-234
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Prolactin Receptor protein is labelled with Fc Tag.
- Purpose
- Recombinant human PRLR protein with C-terminal human Fc tag
- Specificity
- PRLR (Gln25-Asp234) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product PRLR Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- Prolactin Receptor (PRLR)
- Alternative Name
- PRLR (PRLR Products)
- Synonyms
- hPRLrI Protein, PRL-R Protein, prlr Protein, PRLRb Protein, PRLR Protein, tprlr Protein, DKFZp469D061 Protein, RATPRLR Protein, AI987712 Protein, Pr-1 Protein, Pr-3 Protein, Prlr-rs1 Protein, wu:fj65c07 Protein, prolactin receptor Protein, prolactin receptor L homeolog Protein, prolactin receptor S homeolog Protein, prolactin receptor a Protein, PRLR Protein, prlr.L Protein, prlr.S Protein, PR Protein, prlr Protein, Prlr Protein, prlra Protein
- Background
- This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011]
- Molecular Weight
- predicted molecular mass of 50.5 kDa after removal of the signal peptide. The apparent molecular mass of PRLR-hFc is 55-70 kDa due to glycosylation.
- UniProt
- P16471
- Pathways
- JAK-STAT Signaling, Response to Growth Hormone Stimulus
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