RAGE Protein (AA 27-340) (His tag)
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- Target See all RAGE (AGER) Proteins
- RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 27-340
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This RAGE protein is labelled with His tag.
- Purpose
- Recombinant human RAGE protein with C-terminal 6xHis tag
- Specificity
- RAGE (Thr27-Thr340) 6xHis tag
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product AGER Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
- Alternative Name
- RAGE (AGER Products)
- Synonyms
- RAGE Protein, AGER Protein, advanced glycosylation end-product specific receptor Protein, advanced glycosylation end product-specific receptor Protein, MAPK/MAK/MRK overlapping kinase Protein, AGER Protein, Ager Protein, LOC719012 Protein
- Background
- The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847). [provided by RefSeq, May 2011]
- Molecular Weight
- predicted molecular mass of 34.2 kDa after removal of the signal peptide. The apparent molecular mass of RAGE-His is 35-55 kDa due to glycosylation.
- UniProt
- Q15109
- Pathways
- Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteins
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