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IL-31 Protein (AA 24-164) (Fc Tag)

IL31 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7490875
  • Target See all IL-31 (IL31) Proteins
    IL-31 (IL31) (Interleukin 31 (IL31))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 24-164
    Origin
    • 11
    • 3
    • 2
    • 2
    • 1
    Human
    Source
    • 11
    • 6
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IL-31 protein is labelled with Fc Tag.
    Purpose
    Recombinant human IL31 protein with C-terminal human Fc tag
    Specificity
    IL31 (Ser24-Thr164) hFc (Glu99-Ala330)
    Characteristics
    Extracellular Domain Protein
    Purification
    Purified from cell culture supernatant by affinity chromatography
    Purity
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product IL31 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    IL-31 (IL31) (Interleukin 31 (IL31))
    Alternative Name
    IL31 (IL31 Products)
    Synonyms
    IL-31 Protein, 1700013B14Rik Protein, IL31 Protein, interleukin 31 Protein, IL31 Protein, Il31 Protein
    Background
    IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM, Mar 2008]
    Molecular Weight
    predicted molecular mass of 42 kDa after removal of the signal peptide. The apparent molecular mass of IL31-hFc is 35-55 kDa due to glycosylation.
    UniProt
    Q6EBC2
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