Glucagon Receptor Protein (GCGR) (AA 26-136) (Fc Tag)

Catalog No. ABIN7490795

Product Details

Target: Glucagon Receptor (GCGR)

Protein Type: Recombinant

Protein Characteristics: AA 26-136

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This Glucagon Receptor protein is labelled with Fc Tag.

Purpose: Recombinant human GCGR protein with C-terminal human Fc tag

Specificity: GCGR (Ala26-Lys136) hFc (Glu99-Ala330)

Characteristics: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: Glucagon Receptor (GCGR)

Alternative Name: GCGR (GCGR Products)

Synonyms: GCGR Protein, GGR Protein, GR Protein, glucagon receptor Protein, GCGR Protein, Gcgr Protein

Background: The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).[provided by RefSeq, Jan 2010]

Molecular Weight: predicted molecular mass of 39.2 kDa after removal of the signal peptide. The apparent molecular mass of GCGR-hFc is 55-70 kDa due to glycosylation.

UniProt: P47871

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process