HPSE Protein (AA 36-543) (His tag)
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- Target See all HPSE Proteins
- HPSE (Heparanase (HPSE))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 36-543
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This HPSE protein is labelled with His tag.
- Purpose
- Recombinant human HPSE protein with C-terminal 6xHis tag
- Specificity
- HPSE (Gln36-Ile543) 6xHis tag
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product HPSE Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- HPSE (Heparanase (HPSE))
- Alternative Name
- HPSE (HPSE Products)
- Synonyms
- im:7144134 Protein, hpa Protein, hpa1 Protein, hpr1 Protein, hpse1 Protein, hse1 Protein, HPSE Protein, HPA Protein, HPA1 Protein, HPR1 Protein, HPSE1 Protein, HSE1 Protein, Hpa Protein, Hpr1 Protein, Hep Protein, heparanase Protein, HPSE Protein, hpse Protein, Hpse Protein
- Background
- Heparan sulfate proteoglycans are major components of the basement membrane and extracellular matrix. The protein encoded by this gene is an enzyme that cleaves heparan sulfate proteoglycans to permit cell movement through remodeling of the extracellular matrix. In addition, this cleavage can release bioactive molecules from the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
- Molecular Weight
- predicted molecular mass of 58.4 kDa after removal of the signal peptide. The apparent molecular mass of HPSE-His is 55-70 kDa due to glycosylation.
- UniProt
- Q9Y251
- Pathways
- Glycosaminoglycan Metabolic Process
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