ITGA2 Protein (AA 30-1132) (His tag)
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- Target See all ITGA2 Proteins
- ITGA2 (Integrin alpha 2 (ITGA2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 30-1132
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ITGA2 protein is labelled with His tag.
- Purpose
- Recombinant human ITGA2 Protein with C-terminal 6xHis tag
- Specificity
- ITGA2 (Thr30-Thr1132) 6xHis tag
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product ITGA2 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- ITGA2 (Integrin alpha 2 (ITGA2))
- Alternative Name
- ITGA2 (ITGA2 Products)
- Synonyms
- BR Protein, CD49B Protein, GPIa Protein, HPA-5 Protein, VLA-2 Protein, VLAA2 Protein, DX5 Protein, integrin subunit alpha 2 Protein, integrin alpha 2 Protein, ITGA2 Protein, Itga2 Protein
- Background
- This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
- Molecular Weight
- predicted molecular mass of 121.8 kDa after removal of the signal peptide. The apparent molecular mass of ITGA2-His is 130-250 kDa due to glycosylation.
- UniProt
- P17301
- Pathways
- CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
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