MMP13 Protein (AA 20-148) (Fc Tag)
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- Target See all MMP13 Proteins
- MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 20-148
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MMP13 protein is labelled with Fc Tag.
- Purpose
- Recombinant mouse MMP13 protein with C-terminal human Fc tag
- Specificity
- Mouse MMP13 (Leu20-Arg148) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))
- Alternative Name
- MMP13 (MMP13 Products)
- Synonyms
- CLG3 Protein, MANDP1 Protein, Clg Protein, MMP-13 Protein, Mmp1 Protein, cb1034 Protein, mmp13 Protein, gene A Protein, xCol Protein, xcl3 Protein, MMP13 Protein, MGC108008 Protein, matrix metallopeptidase 13 Protein, matrix metallopeptidase 13a Protein, matrix metallopeptidase 13 (collagenase 3) like S homeolog Protein, matrix metallopeptidase 13 (collagenase 3) Protein, matrix metalloproteinase 13 Protein, matrix metallopeptidase 13 (collagenase 3) like L homeolog Protein, MMP13 Protein, Mmp13 Protein, mmp13a Protein, mmp13l.S Protein, mmp13 Protein, LOC100136348 Protein, mmp13l.L Protein
- Background
- This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]
- Molecular Weight
- predicted molecular mass of 78.1 kDa after removal of the signal peptide. The apparent molecular mass of mMMP13-hFc is 70-100 kDa due to glycosylation.
- UniProt
- P33435
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