HAVCR1 Protein (AA 23-342) (His tag)
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- Target See all HAVCR1 Proteins
- HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-342
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Origin
- Cynomolgus
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This HAVCR1 protein is labelled with His tag.
- Purpose
- Cynomolgus TIM-1/HAVCR1 Protein
- Sequence
- Val23-Gly342
- Characteristics
- Recombinant Cynomolgus TIM-1/HAVCR1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Val23-Gly342.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product HAVCR1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))
- Alternative Name
- TIM-1 (HAVCR1 Products)
- Synonyms
- HAVCR Protein, HAVCR-1 Protein, KIM-1 Protein, KIM1 Protein, TIM Protein, TIM-1 Protein, TIM1 Protein, TIMD-1 Protein, TIMD1 Protein, Kim1 Protein, HAVCR1 Protein, LOC100226241 Protein, AI503787 Protein, Tim1 Protein, Timd1 Protein, hepatitis A virus cellular receptor 1 Protein, hepatitis A virus cellular receptor 1 homolog Protein, HAVCR1 Protein, Havcr1 Protein, LOC100226241 Protein
- Background
- Kidney injury molecule 1 (KIM-1, also known as TIM-1) is markedly upregulated in the proximal tubule after injury and is maladaptive when chronically expressed. KIM-1-mediated epithelial cell phagocytosis of apoptotic cells protects the kidney after acute injury by downregulating innate immunity and inflammation.
- Molecular Weight
- 35.25 kDa. Due to glycosylation, the protein migrates to 100-150 kDa based on Tris-Bis PAGE result.
- UniProt
- A0A2K5WXJ6
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