SARS-CoV-2 Spike S2 Protein (BA.1 - Omicron) (Biotin,His-Avi Tag)
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- Target See all SARS-CoV-2 Spike S2 Proteins
- SARS-CoV-2 Spike S2
- Protein Type
- Recombinant
- Protein Characteristics
- BA.1 - Omicron
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Origin
- SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SARS-CoV-2 Spike S2 protein is labelled with Biotin,His-Avi Tag.
- Purpose
- Biotinylated SARS-CoV-2 Spike S2 protein, His,Avitag™ (BA.1/Omicron)
- Sequence
- Ser 686 - Pro 1213
- Characteristics
- Biotinylated SARS-CoV-2 Spike S2 protein, His,Avitag™ (BA.1/Omicron) is expressed from human 293 cells (HEK293). It contains AA Ser Ser 686 - Pro 1213 (Accession # QHD43416.1 (N764K, D796Y, N856K, Q954H, N969K, L981F, F817P, A892P, A899P, A942P, K986P, V987P). The mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.1, GISAID clade: GRA, Nextstrain clade: 21K). Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) are introduced to prevent the formation of aggregates in the course of protein production.
- Purity
- 95,00 %
- Endotoxin Level
- 1.0 EU per μg
- Top Product
- Discover our top product SARS-CoV-2 Spike S2 Protein
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- Comment
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This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 61.7 kDa. The protein migrates as 80-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
- Storage Comment
- -20°C
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- Target
- SARS-CoV-2 Spike S2
- Alternative Name
- SARS-CoV-2 Spike S2 protein (SARS-CoV-2 Spike S2 Products)
- Synonyms
- E2 Protein, Surface Glycoprotein Protein, S Protein
- Target Type
- Viral Protein
- Background
- Synonyms:Spike,S2 protein,Spike glycoprotein Subunit2,S glycoprotein Subunit2,Spike protein S2,Description:It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
- Molecular Weight
- 61.7 kDa
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