LGR5 Protein (His tag)
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- Target See all LGR5 Proteins
- LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
- Protein Type
- Recombinant
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Origin
- Cynomolgus
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LGR5 protein is labelled with His tag.
- Purpose
- Cynomolgus LGR5 / GPR49 protein, His Tag
- Sequence
- Ser 22 - Gly 557
- Characteristics
- Cynomolgus LGR5, His Tag is expressed from human 293 cells (HEK293). It contains AA Ser 22 - Gly 557 (Accession # G7PI19-1).
- Purity
- 95,00 %
- Endotoxin Level
- 1.0 EU per μg
- Top Product
- Discover our top product LGR5 Protein
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Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 22-543) protein (Fc Tag)
LGR5 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) proteinLGR5 Origin: Human Host: HEK-293 Cells Synthetic Nanodisc
Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 22-561) (Active) protein (His tag)LGR5 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 22-561) protein (His tag)LGR5 Origin: Human Host: Yeast Recombinant > 90 % SDS
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- Comment
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This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 61.7 kDa. The protein migrates as 66-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
- Storage Comment
- -20°C
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- Target
- LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
- Alternative Name
- LGR5 (LGR5 Products)
- Synonyms
- lgr5-a Protein, lgr5a Protein, FEX Protein, Gpr49 Protein, GPR49 Protein, GPR67 Protein, GRP49 Protein, HG38 Protein, leucine-rich repeat containing G protein-coupled receptor 5 L homeolog Protein, leucine rich repeat containing G protein coupled receptor 5 Protein, leucine rich repeat containing G protein-coupled receptor 5 Protein, lgr5.L Protein, Lgr5 Protein, LGR5 Protein
- Background
- Synonyms:LGR5, GPR49, GPR67, G-protein coupled receptor 49, G-protein coupled receptor 67, G-protein coupled receptor HG38, Leucine-rich repeat-containing G-protein coupled receptor 5,Description:LGR5 (also known as GPR49) is a seven-transmembrane protein of the class A Rhodopsin-like family of GPCRs. LGR5 and LGR4 bind the R-spondins with high affinity and mediate the potentiation of Wnt/β-catenin signaling by enhancing Wnt-induced LRP6 phosphorylation. The LGR5/RSPO complex could promote Wnt signalling via the neutralization of two transmembrane E3 ligases, RNF43 and ZNRF3.
- Molecular Weight
- 61.7 kDa
- Pathways
- WNT Signaling
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