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IL12RB1 Protein (Biotin,His-Avi Tag)

IL12RB1 Origin: Mouse Host: HEK-293 Cells Recombinant 90,00 %
Catalog No. ABIN7447936
  • Target See all IL12RB1 Proteins
    IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
    Protein Type
    Recombinant
    Origin
    • 13
    • 1
    • 1
    Mouse
    Source
    • 9
    • 3
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This IL12RB1 protein is labelled with Biotin,His-Avi Tag.
    Purpose
    Biotinylated Mouse IL-12 R beta 1 / CD212 Protein, His,Avitag™
    Sequence
    Gln 20 - Ser 565
    Characteristics
    Biotinylated Mouse IL-12 R beta 1, His,Avitag is expressed from human 293 cells (HEK293). It contains AA Gln 20 - Ser 565 (Accession # Q60837-1).
    Purity
    90,00 %
    Endotoxin Level
    1.0 EU per μg
    Top Product
    Discover our top product IL12RB1 Protein
  • Comment

    This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 64.7 kDa. The protein migrates as 93-103 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Storage
    -20 °C
    Storage Comment
    -20°C
  • Target
    IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
    Alternative Name
    IL-12 R beta 1 (IL12RB1 Products)
    Synonyms
    Il12rb Protein, IL12RB1 Protein, IL-12R Protein, CD212 Protein, IL-12R-BETA1 Protein, IL12RB Protein, IL-12R[b] Protein, interleukin 12 receptor subunit beta 1 Protein, interleukin 12 receptor, beta 1 Protein, Il12rb1 Protein, IL12RB1 Protein
    Background
    Synonyms:IL-12 R beta 1,IL12RB1,CD212,IL12R,IL12RB,IL-12RB1,Description:The human IL-12 R subunit is a member of the cytokine receptor superfamily and the functional high-affinity IL-12R is composed of at least two beta-type cytokine receptor subunits, each independently exhibiting a low affinity for IL-12. IL-12 R beta 1 (Interleukin-12 receptor subunit beta-1) is also known as IL-12RB1, CD212. Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.
    Molecular Weight
    64.7 kDa
    NCBI Accession
    NP_005526
    Pathways
    JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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