IgG1 Protein (Asn317Phe-Mutant, Cys103Ser-Mutant, His316Lys-Mutant, Met135Tyr-Mutant, Ser137Thr-Mutant, Thr139Glu-Mutant) (His tag)
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- Target See all IgG1 Proteins
- IgG1
- Protein Type
- Recombinant
- Protein Characteristics
- Asn317Phe-Mutant, Cys103Ser-Mutant, His316Lys-Mutant, Met135Tyr-Mutant, Ser137Thr-Mutant, Thr139Glu-Mutant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IgG1 protein is labelled with His tag.
- Purpose
- Human IgG1 Fc (C103S, M135Y, S137T, T139E, H316K, N317F) Protein, His Tag
- Sequence
- Glu 99 - Lys 330
- Characteristics
- Human IgG1 Fc (C103S, M135Y, S137T, T139E, H316K, N317F), His Tag is expressed from human 293 cells (HEK293). It contains AA Glu 99 - Lys 330 (Accession # P01857-1 (C103S, M135Y, S137T, T139E, H316K, N317F).
- Purity
- 95,00 %
- Endotoxin Level
- 1.0 EU per μg
- Top Product
- Discover our top product IgG1 Protein
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- Comment
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This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 28.1 kDa. The protein migrates as 30-32 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 51 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
- Storage
- -20 °C
- Storage Comment
- -20°C
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- Target
- IgG1
- Abstract
- IgG1 Products
- Synonyms
- IgG1 Protein, Igh-4 Protein, VH7183 Protein, immunoglobulin heavy constant gamma 1 (G1m marker) Protein, Ighg1 Protein
- Target Type
- Antibody
- Background
- Synonyms:IgG1,Description:Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
- Molecular Weight
- 28.1 kDa
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