CD79a Protein (His tag)
-
- Target See all CD79a (CD79A) Proteins
- CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
- Protein Type
- Recombinant
-
Origin
- Cynomolgus
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD79a protein is labelled with His tag.
- Purpose
- Cynomolgus CD79A Protein, His Tag
- Sequence
- Leu 33 - Arg 142
- Characteristics
- Cynomolgus CD79A, His Tag is expressed from human 293 cells (HEK293). It contains AA Leu 33 - Arg 142 (Accession # XP_045235481.1).
- Purity
- 90,00 %
- Endotoxin Level
- 1.0 EU per μg
- Top Product
- Discover our top product CD79A Protein
-
-
- Comment
-
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 14.4 kDa. The protein migrates as 27-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- RT
- Storage Comment
- RT
-
- Target
- CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
- Alternative Name
- CD79A (CD79A Products)
- Synonyms
- CD79A Protein, Ig-alpha Protein, Iga Protein, Igalpha Protein, Ly-54 Protein, Ly54 Protein, mb-1 Protein, IGA Protein, MB-1 Protein, IG-alpha Protein, CD79a molecule Protein, CD79A antigen (immunoglobulin-associated alpha) Protein, Cd79a molecule-like Protein, CD79A Protein, Cd79a Protein, Cd79al Protein
- Background
- Synonyms:CD79A, CD79a, B-cell antigen receptor complex-associated protein alpha chain, B-cell antigen receptor complex-associated protein alpha chain, Ig-alpha, MB-1 membrane glycoprotein, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated p,Description:B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain(CD79a), also known as CD79α, IgM-α, Ig-α and mb-1, which is a signaling component of the preB cell receptor (preBCR). Covalently linked CD79a and CD79b heterodimer constitutes the B cell antigen receptor (BCR) with membrane immunoglobulin (mIg) in a non-covalent association. CD79a is required in cooperation with CD79b for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR), leading to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79a is also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells.
- Molecular Weight
- 14.4 kDa
- NCBI Accession
- XP_045235481
- Pathways
- BCR Signaling
-