TIMP2 Protein (AA 27-220) (His tag)
-
- Target See all TIMP2 Proteins
- TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 27-220
-
Origin
- Mouse
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TIMP2 protein is labelled with His tag.
- Purpose
- Mouse TIMP-2 Protein
- Sequence
- Cys27-Pro220
- Characteristics
- Recombinant Mouse TIMP-2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Cys27-Pro220.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product TIMP2 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))
- Alternative Name
- TIMP-2 (TIMP2 Products)
- Synonyms
- CSC-21K Protein, DDC8 Protein, timp2l Protein, zgc:65967 Protein, zgc:85799 Protein, D11Bwg1104e Protein, Timp-2 Protein, TIMP-2 Protein, etID32613.12 Protein, fa96h09 Protein, timp2 Protein, wu:fa96h09 Protein, zgc:136726 Protein, TIMP metallopeptidase inhibitor 2 Protein, TIMP metallopeptidase inhibitor 2b Protein, tissue inhibitor of metalloproteinase 2 Protein, TIMP metallopeptidase inhibitor 2a Protein, TIMP metallopeptidase inhibitor 2 L homeolog Protein, TIMP2 Protein, timp2b Protein, Timp2 Protein, timp2a Protein, timp2.L Protein
- Background
- Tissue inhibitors of metalloproteinases or TIMPs are a family of proteins that regulate the activation and proteolytic activity of the zinc enzymes known as matrix metalloproteinases (MMPs).TIMP-2 is a non N-glycosylated protein with a molecular mass of 22 kDa produced by a wide range of cell types, which inhibits MMPs non-covalently by the formation of binary complexes. TIMP-2 also has erythroid-potentiating and cell growth promoting activities.
- Molecular Weight
- 22.8 kDa. Due to glycosylation, the protein migrates to 24-26 kDa based on Tris-Bis PAGE result.
- UniProt
- P25785
- Pathways
- cAMP Metabolic Process
-