THSD7A Protein (AA 48-1607) (His tag)
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- Target See all THSD7A Proteins
- THSD7A (Thrombospondin, Type I, Domain Containing 7A (THSD7A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 48-1607
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This THSD7A protein is labelled with His tag.
- Purpose
- Human THSD7A Protein
- Sequence
- Ala48-Trp1607
- Characteristics
- Recombinant Human THSD7A Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala48-Trp1607.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- THSD7A (Thrombospondin, Type I, Domain Containing 7A (THSD7A))
- Alternative Name
- THSD7A (THSD7A Products)
- Synonyms
- Gm837 Protein, thrombospondin type 1 domain containing 7A Protein, thrombospondin, type I, domain containing 7A Protein, THSD7A Protein, Thsd7a Protein
- Background
- Thrombospondin type I domain-containing 7A (THSD7A), is a specific autoantigen of adult idiopathic membranous nephropathy (IMN), whose circulating antibody (THSD7A-AB) represents a promising biomarker for diagnosis of IMN.
- Molecular Weight
- 176.22 kDa. Due to glycosylation, the protein migrates to 180-240 kDa based on Tris-Bis PAGE result.
- UniProt
- Q9UPZ6
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