TGFB2 Protein (AA 303-414)
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- Target See all TGFB2 Proteins
- TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 303-414
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human Mature TGF beta 2 Protein
- Sequence
- Ala303-Ser414
- Characteristics
- Recombinant Human Mature TGF beta 2 Protein is expressed from HEK293 without tag. It contains Ala303-Ser414.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human Mature TGF beta 2, No Tag at 2μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Human TGF-beta RII, mFc Tag with the EC50 of 0.11μg/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product TGFB2 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in 4 mM HCl.
- Buffer
- Lyophilized from 0.22μm filtered solution in 4 mM HCl. Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))
- Alternative Name
- TGF beta 2 (TGFB2 Products)
- Synonyms
- LDS4 Protein, TGF-beta2 Protein, tgf-beta2 Protein, tgfb2-A Protein, BB105277 Protein, Tgf-beta2 Protein, Tgfb-2 Protein, TGF-beta 2 Protein, Tgfbr2T Protein, TGFB2 Protein, TGFbeta2 Protein, MGF Protein, TGF-B2 Protein, transforming growth factor beta 2 Protein, transforming growth factor beta 2 L homeolog Protein, transforming growth factor, beta 2 Protein, transforming growth factor, beta receptor 2 Protein, TGFB2 Protein, tgfb2.L Protein, Tgfb2 Protein, Tgfbr2 Protein, tgfb2 Protein
- Background
- Transforming growth factor beta(2) (TGF-beta(2)), a growth regulator of human lens epithelial cells (HLECs), also regulates the death of these cells. TGF-beta(2)-induced apoptosis in HLECs was preceded by an induction of reactive oxygen species (ROS) and a decrease in glutathione in the intracellular content, indicating that this factor induces oxidative stress in HLECs.
- Molecular Weight
- 12.7 kDa. Due to glycosylation, the protein migrates to 13-15 kDa based on Tris-Bis PAGE result.
- Pathways
- Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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