TFPI2 Protein (AA 23-213) (His tag)
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- Target See all TFPI2 Proteins
- TFPI2 (Tissue Factor Pathway Inhibitor 2 (TFPI2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-213
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TFPI2 protein is labelled with His tag.
- Purpose
- Human TFPI-2 Protein
- Sequence
- Asp23-Lys213.
- Characteristics
- Recombinant Human TFPI-2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asp23-Lys213.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product TFPI2 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- TFPI2 (Tissue Factor Pathway Inhibitor 2 (TFPI2))
- Alternative Name
- TFPI-2 (TFPI2 Products)
- Synonyms
- MGC68843 Protein, TFPI2 Protein, MGC108301 Protein, si:ch211-262k23.2 Protein, tfpi2 Protein, PP5 Protein, REF1 Protein, TFPI-2 Protein, AV000670 Protein, PP5/TFPI-2 Protein, tissue factor pathway inhibitor 2 L homeolog Protein, tissue factor pathway inhibitor 2 Protein, tfpi2.L Protein, TFPI2 Protein, tfpi2 Protein, Tfpi2 Protein
- Background
- Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix. Moreover, in sputum from cystic fibrosis patients TFPI-2 C-terminal fragments are generated and found associated with immunoglobulins. Together our data describe a previously unknown host defense mechanism and therapeutic importance of TFPI-2 against invading Gram-negative bacterial pathogens.
- Molecular Weight
- 22.9 kDa. Due to glycosylation, the protein migrates to 30-35 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- NP_006519
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