PILRA Protein (AA 32-197) (His tag)
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- Target See all PILRA Proteins
- PILRA (Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 32-197
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PILRA protein is labelled with His tag.
- Purpose
- Mouse PILRA Protein
- Sequence
- Glu32-Val197
- Characteristics
- Recombinant Mouse PILRA Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu32-Val197.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product PILRA Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- PILRA (Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA))
- Alternative Name
- PILRA (PILRA Products)
- Synonyms
- PILRA Protein, FDF03 Protein, AV021745 Protein, RGD1562847 Protein, paired immunoglobin like type 2 receptor alpha Protein, paired immunoglobulin-like type 2 receptor alpha Protein, paired immunoglobin-like type 2 receptor alpha Protein, PILRA Protein, LOC489841 Protein, Pilra Protein
- Background
- Alzheimer's disease (AD) is a neurodegenerative disease characterized by a progressive decline in cognitive performance, Mild Cognitive Impairment (MCI) is instead an objective decline in cognitive performance that does not reach pathology. Paired immunoglobulin-like type 2 receptor alpha (PILRA) is a cell surface inhibitory receptor that was recently suggested to be involved in AD pathogenesis. In particular, the arginine-to-glycine substitution in position 78 (R78, rs1859788) was shown to be protective against AD.
- Molecular Weight
- 19.71 kDa. Due to glycosylation, the protein migrates to 43-60 kDa based on Tris-Bis PAGE result.
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