PLA2G7 Protein (AA 22-441) (His tag)
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- Target See all PLA2G7 (Lp-PLA2) Proteins
- PLA2G7 (Lp-PLA2) (Lipoprotein-Associated phospholipase A2 (Lp-PLA2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-441
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PLA2G7 protein is labelled with His tag.
- Purpose
- Human PLA2G7 Protein
- Sequence
- Phe22-Asn441
- Characteristics
- Recombinant Human PLA2G7 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe22-Asn441.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product Lp-PLA2 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in 50 mM NaAc, 150 mM NaCl, 10 % Glycerol ( pH 5.0).
- Storage
- -80 °C
- Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- PLA2G7 (Lp-PLA2) (Lipoprotein-Associated phospholipase A2 (Lp-PLA2))
- Alternative Name
- PLA2G7 (Lp-PLA2 Products)
- Synonyms
- LDL-PLA2 Protein, LP-PLA2 Protein, PAFAD Protein, PAFAH Protein, Lp-PLA2 Protein, PAF-AH Protein, R75400 Protein, zgc:77563 Protein, phospholipase A2 group VII Protein, phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) Protein, PLA2G7 Protein, Pla2g7 Protein, pla2g7 Protein
- Background
- Endogenous PLA2G7 transcription levels were found to be significantly lower in vascular related cell lines than in the other cell lines. Luciferase reporter gene assays indicated that gene activity was significantly enhanced by PLA2G7 promoter fragment. LA2G7 transcription was found to be up-regulated with the treatment of DAC. The 17-β-estradiol was found to down-regulate PLA2G7 transcription in all the cell lines.
- Molecular Weight
- 48.9 kDa. Due to glycosylation, the protein migrates to 49-60 kDa based on Tris-Bis PAGE result.
- UniProt
- Q13093
- Pathways
- Peptide Hormone Metabolism
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