PSCA Protein (AA 12-86) (Fc Tag)
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- Target See all PSCA Proteins
- PSCA (Prostate Stem Cell Antigen (PSCA))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 12-86
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PSCA protein is labelled with Fc Tag.
- Purpose
- Human PSCA Protein
- Sequence
- Leu12-Ser86
- Characteristics
- Recombinant Human PSCA Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Leu12-Ser86.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human PSCA, hFc Tag at 2μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Anti-PSCA Ab., hFc Tag with the EC50 of 38.5ng/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product PSCA Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- PSCA (Prostate Stem Cell Antigen (PSCA))
- Alternative Name
- PSCA (PSCA Products)
- Synonyms
- PRO232 Protein, 2210408B04Rik Protein, PSCA Protein, prostate stem cell antigen Protein, PSCA Protein, Psca Protein, LOC482068 Protein
- Background
- Gastric cancer is a deadly malignancy and is a prognostically unfavorable entity with restricted therapeutic strategies available. Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell surface protein widely expressed in bladder, prostate, and pancreatic cancers. Existing studies have thoroughly recognized the availability of utilizing anti-PSCA CAR-T cells in the treatment of metastatic prostate cancer and non-small-cell lung cancer.
- Molecular Weight
- 34.3 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
- UniProt
- O43653
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