PLAUR Protein (AA 23-305) (Fc Tag)
-
- Target See all PLAUR Proteins
- PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-305
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PLAUR protein is labelled with Fc Tag.
- Purpose
- Human uPAR/PLAUR Protein
- Sequence
- Leu23-Gly305
- Characteristics
- Recombinant Human uPAR/PLAUR Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu23-Gly305.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human PLAU, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Human uPAR, hFc Tag with the EC50 of 10.3ng/ml determined by ELISA. See testing image for detail.
-
-
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
- Storage
- -80 °C
- Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
- Alternative Name
- uPAR (PLAUR Products)
- Synonyms
- Cd87 Protein, u-PAR Protein, uPAR Protein, CD87 Protein, U-PAR Protein, UPAR Protein, URKR Protein, Par Protein, Plaur3 Protein, uPAR-2 Protein, uPAR-3 Protein, PLAUR Protein, plasminogen activator, urokinase receptor Protein, Plaur Protein, PLAUR Protein
- Background
- The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasminogen.Regulation of the activity of u-PA is also mediated by u-PAR.
- Molecular Weight
- 58.2 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
- Pathways
- Inositol Metabolic Process
-