TNFSF4 Protein (AA 51-198) (Fc Tag)
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- Target See all TNFSF4 Proteins
- TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 51-198
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TNFSF4 protein is labelled with Fc Tag.
- Purpose
- Mouse OX40 Ligand/TNFSF4 Protein
- Sequence
- Ser51-Leu198
- Characteristics
- Recombinant Mouse OX40 Ligand/TNFSF4 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Ser51-Leu198.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Mouse OX40 Ligand at 2μg/ml (100μl/well) on the plate. Dose response curve for Mouse OX40, His Tag with the EC50 3.59μg/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product TNFSF4 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))
- Alternative Name
- OX-40 Ligand (TNFSF4 Products)
- Synonyms
- TNFSF4 Protein, OX40L Protein, TNFRSF4 Protein, CD134L Protein, CD252 Protein, GP34 Protein, OX-40L Protein, OX4OL Protein, TXGP1 Protein, Ath-1 Protein, Ath1 Protein, Ox40l Protein, Txgp1l Protein, gp34 Protein, TNF superfamily member 4 Protein, tumor necrosis factor (ligand) superfamily, member 4 Protein, TNFSF4 Protein, Tnfsf4 Protein
- Background
- Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L),which belongs to the tumor necrosis factor family. It is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation.
- Molecular Weight
- 42.6 kDa. Due to glycosylation, the protein migrates to 52-56 kDa based on Tris-Bis PAGE result.
- UniProt
- P43488
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation, Cancer Immune Checkpoints
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