NRP2 Protein (AA 23-859) (His tag)
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- Target See all NRP2 Proteins
- NRP2 (Neuropilin 2 (NRP2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-859
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NRP2 protein is labelled with His tag.
- Purpose
- Mouse Neuropilin-2 Protein
- Sequence
- Gln23-Leu859
- Characteristics
- Recombinant Mouse Neuropilin-2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln23-Leu859.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product NRP2 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- NRP2 (Neuropilin 2 (NRP2))
- Alternative Name
- Neuropilin-2 (NRP2 Products)
- Synonyms
- NP2 Protein, NPN2 Protein, PRO2714 Protein, VEGF165R2 Protein, 1110048P06Rik Protein, Np-2 Protein, Np2 Protein, Npn-2 Protein, Npn2 Protein, neuropilin-2 Protein, neuropilin 2 Protein, NRP2 Protein, Nrp2 Protein
- Background
- Neuropilins (NRPs) are single transmembrane receptors with short cytoplasmic tails and are dependent on receptors like VEGF receptors or Plexins for signal transduction. NRPs are known to be important in angiogenesis, lymphangiogenesis, and axon guidance. The Neuropilin-family consists of two members, Neuropilin-1 (NRP1) and Neuropilin-2 (NRP2). NRP2 is important for migration, antigen presentation, phagocytosis and cell-cell contact within the immune system. Additionally, posttranslational NRP2 modifications like polysialylation are crucial for the function of some immune cells.
- Molecular Weight
- 95.3 kDa. Due to glycosylation, the protein migrates to 110-116 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- NP_001070871
- Pathways
- Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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