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NKG2C & CD94 (AA 98-231) protein (His-Avi Tag,Biotin)

Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7275331
  • Target
    NKG2C & CD94
    Protein Type
    Recombinant
    Protein Characteristics
    AA 98-231
    Origin
    • 3
    • 1
    Human
    Source
    • 4
    HEK-293 Cells
    Purification tag / Conjugate
    His-Avi Tag,Biotin
    Purpose
    Biotinylated Human NKG2C & CD94 Protein
    Sequence
    Glu98-Leu231 (NKG2C) & Ser34-Ile179 (CD94)
    Specificity
    Uni-Prot: P26717 (NKG2C), Q13241-1 (CD94)
    Characteristics
    Recombinant Biotinylated Human NKG2C & CD94 Protein is expressed from HEK293 with His tag and Avi tag at the N-Terminus.It contains Glu98-Leu231(NKG2C) & Ser34-Ile179(CD94).
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    NKG2C & CD94
    Alternative Name
    NKG2C&CD94
    Background
    NKG2C&CD94 is a C-type lectin heterodimer on NK cells and CD8+ cytotoxic T-cells, it can recognize peptides derived from the intracellular proteins in the context of HLA-E. NKG2C&CD94 itself has no signal transduction function but is an activating receptor on the surface of NK cells that involved in driving the NK-cell expansion.
    Molecular Weight
    15.3kDa (NKG2C)&17.9kDa (CD94). Due to glycosylation, the protein migrates to 25-35 kDa based on Tris-Bis PAGE result.
    UniProt
    P26717
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