Mesothelin Protein (MSLN) (AA 296-580) (FITC,Fc Tag)
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- Target See all Mesothelin (MSLN) Proteins
- Mesothelin (MSLN)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 296-580
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Mesothelin protein is labelled with FITC,Fc Tag.
- Purpose
- FITC-Labeled Human MSLN/Mesothelin Protein
- Sequence
- Glu296-Gly580
- Characteristics
- Recombinant FITC-Labeled Human MSLN/Mesothelin Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Glu296-Gly580.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product MSLN Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
- Storage
- -80 °C
- Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- Mesothelin (MSLN)
- Alternative Name
- MSLN (MSLN Products)
- Synonyms
- MPF Protein, SMRP Protein, MSLN Protein, mesothelin Protein, MSLN Protein, Msln Protein, LOC611363 Protein, LOC100524016 Protein
- Background
- Mesothelin, also known as MSLN, is a protein that in humans is encoded by the MSLN gene.Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31- kDa shed fragment named megakaryocyte-potentiating factor (MPF). Although it has been proposed that mesothelin may be involved in cell adhesion, its biological function is not known.A knockout mouse line that lacks mesothelin reproduces and develops normally.
- Molecular Weight
- 59 kDa. Due to glycosylation, the protein migrates to 68-75 kDa based on Tris-Bis PAGE result.
- Pathways
- EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process
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