MMP8 Protein (AA 21-465) (His tag)
-
- Target See all MMP8 Proteins
- MMP8 (Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-465
-
Origin
- Mouse
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MMP8 protein is labelled with His tag.
- Purpose
- Mouse MMP-8 Protein (pro form)
- Sequence
- Phe21-Ser465
- Characteristics
- Recombinant Mouse MMP-8 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe21-Ser465.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product MMP8 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in 50 mM Tris, 10 mM CaCl2, 150 mM NaCl ( pH 7.5).
- Storage
- -80 °C
- Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- MMP8 (Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8))
- Alternative Name
- MMP-8 (MMP8 Products)
- Synonyms
- MMP8 Protein, BB138268 Protein, CLG1 Protein, HNC Protein, MMP-8 Protein, PMNL-CL Protein, matrix metallopeptidase 8 Protein, neutrophil collagenase Protein, MMP8 Protein, Mmp8 Protein, LOC100339790 Protein
- Background
- Alteration of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) expression has been studied for various cardiac diseases, including dilated cardiomyopathy (DCM), with the significance of surrogate markers of extracellular matrix (ECM) remodeling. MMP-8 was identified only in myocardiocytes, while MMP-9 and TIMP-2 were present in both myocardiocytes and stroma, but with different intensity. The increasing intensity of MMP-8 and TIMP-2 immunoreactions was significantly associated with low HCS.
- Molecular Weight
- 51.9 kDa. Due to glycosylation, the protein migrates to 65-70 kDa based on Tris-Bis PAGE result.
- UniProt
- O70138
-