Midkine Protein (AA 23-140) (His tag)
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- Target See all Midkine (MDK) Proteins
- Midkine (MDK) (Midkine (Neurite Growth-Promoting Factor 2) (MDK))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-140
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Midkine protein is labelled with His tag.
- Purpose
- Mouse Midkine Protein
- Sequence
- Lys23-Asp140
- Characteristics
- Recombinant Mouse Midkine Protein is expressed from E.coli with His tag at the N-Terminus.It contains Lys23-Asp140.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product MDK Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in PBS, 350 mM NaCl, 200 mM L-arginine ( pH 7.4).
- Storage
- -80 °C
- Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- Midkine (MDK) (Midkine (Neurite Growth-Promoting Factor 2) (MDK))
- Alternative Name
- Midkine (MDK Products)
- Synonyms
- ARAP Protein, MK Protein, NEGF2 Protein, Mek Protein, MK-B Protein, PTF-alpha-1 Protein, mdk Protein, midkine Protein, negf2 Protein, RIHB Protein, cb518 Protein, fb79b05 Protein, fj33b02 Protein, fj48a12 Protein, mdk2 Protein, plei2 Protein, wu:fb79b05 Protein, wu:fj33b02 Protein, wu:fj48a12 Protein, MK-A Protein, PTF-alpha-2 Protein, X-PTF-alpha1 Protein, XMK Protein, mdk-a Protein, mdk-b Protein, midkine Protein, midkine L homeolog Protein, midkine (neurite growth-promoting factor 2) Protein, midkine b Protein, midkine S homeolog Protein, MDK Protein, Mdk Protein, mdk.L Protein, mdkb Protein, mdk.S Protein
- Background
- Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis.
- Molecular Weight
- 14.03 kDa. The protein migrates to 17-20 kDa based on Tris-Bis PAGE result.
- UniProt
- P12025
- Pathways
- RTK Signaling, M Phase, Skeletal Muscle Fiber Development
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