MFAP5 Protein (AA 22-173) (Fc Tag)
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- Target See all MFAP5 Proteins
- MFAP5 (Microfibrillar Associated Protein 5 (MFAP5))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-173
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MFAP5 protein is labelled with Fc Tag.
- Purpose
- Human MFAP5 Protein
- Sequence
- Ile22-Leu173
- Characteristics
- Recombinant Human MFAP5 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ile22-Leu173.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
- Storage
- -80 °C
- Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- MFAP5 (Microfibrillar Associated Protein 5 (MFAP5))
- Alternative Name
- MFAP5 (MFAP5 Products)
- Synonyms
- MFAP5 Protein, MAGP2 Protein, MP25 Protein, MAGP-2 Protein, microfibrillar associated protein 5 Protein, microfibril associated protein 5 Protein, MFAP5 Protein, Mfap5 Protein
- Background
- Human basal-like breast cancer (BLBC) is an aggressive malignancy with poor prognosis. Since most current treatments are ineffective, there is an urgent need to identify therapeutic targets for BLBC. Microfibrillar-associated protein 5 (MFAP5) plays an important role in the integration of elastic microfibers and the regulation of endothelial cell behaviors.MFAP5 was significantly overexpressed in BLBC tissues and associated with poor metastasis-free survival of patients with BLBC.
- Molecular Weight
- 44.1 kDa. Due to furin cleavage and glycosylation, the protein migrates to 32-38 kDa and 55-65 kDa based on Tris-Bis PAGE result.
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