LYPD3 Protein (AA 31-286) (His tag)
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- Target See all LYPD3 products
- LYPD3 (LY6/PLAUR Domain Containing 3 (LYPD3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 31-286
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LYPD3 protein is labelled with His tag.
- Purpose
- Human LYPD3 Protein
- Sequence
- Leu31-His286
- Characteristics
- Recombinant Human LYPD3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu31-His286.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human LYPD3, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-LYPD3 Ab., hFc Tag with the EC50 of 11.6ng/ml determined by ELISA. See testing image for detail.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- LYPD3 (LY6/PLAUR Domain Containing 3 (LYPD3))
- Alternative Name
- LYPD3 (LYPD3 Products)
- Synonyms
- LYPD3 Protein, MGC139913 Protein, C4.4A Protein, 2310061G07Rik Protein, C4.4a Protein, LY6/PLAUR domain containing 3 Protein, Ly6/Plaur domain containing 3 Protein, LYPD3 Protein, Lypd3 Protein
- Background
- Aberrant expression of LYPD3 plays an oncogenic role in several types of cancer. LYPD3 was highly expressed in LUAD tumor compared with paracancerous tissues.Furthermore, the expression of LYPD3 was able to be regulated by the methylation in LYPD3 promoter region, which was positively associated with the overall survival. LYPD3 might affect the clinical manifestations of LUAD by regulating the P53 signaling pathway.
- Molecular Weight
- 27.8 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
- UniProt
- O95274
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