LILRB4 Protein (AA 119-259) (His-Avi Tag,Biotin)
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- Target See all LILRB4 products
- LILRB4 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 119-259
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LILRB4 protein is labelled with His-Avi Tag,Biotin.
- Purpose
- Biotinylated Human LILRB4/CD85k/ILT3 SR & Domain 2 Protein
- Sequence
- Gly119-Glu259
- Characteristics
- Recombinant Biotinylated Human LILRB4/CD85k/ILT3 Domain 2 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly119-Glu259.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
- Storage
- -80 °C
- Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- LILRB4 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4))
- Alternative Name
- LILRB4 (LILRB4 Products)
- Synonyms
- CD85K Protein, ILT-3 Protein, ILT3 Protein, LIR-5 Protein, LIR5 Protein, Gp49b Protein, HM18 Protein, gp49 Protein, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 Protein, leukocyte immunoglobulin like receptor B4 Protein, leukocyte immunoglobulin-like receptor, subfamily B, member 4A Protein, LILRB4 Protein, Lilrb4a Protein
- Background
- LILRB4,also known as CD85k and LIR-5, ILT3, is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles.
- Molecular Weight
- 18.16 kDa. Due to glycosylation, the protein migrates to 32-45 kDa based on Tris-Bis PAGE result.
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