IL13 Receptor alpha 1 Protein (AA 25-341) (His tag)
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- Target See all IL13 Receptor alpha 1 (IL13RA1) Proteins
- IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 25-341
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Origin
- Cynomolgus
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL13 Receptor alpha 1 protein is labelled with His tag.
- Purpose
- Cynomolgus IL-13Ra1 Protein
- Sequence
- Ala25-Thr341
- Characteristics
- Recombinant Cynomolgus IL-13Ra1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala25-Thr341.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 21.16 nM as determined in SPR assay (Biacore T200). See testing image for detail.
- Top Product
- Discover our top product IL13RA1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))
- Alternative Name
- IL-13Ra1 (IL13RA1 Products)
- Synonyms
- CD213A2 Protein, CT19 Protein, IL-13R Protein, IL13BP Protein, CD213A1 Protein, IL-13Ra Protein, NR4 Protein, AI882074 Protein, CD213a1 Protein, IL-13r[a] Protein, Il13ra Protein, IL13RA1 Protein, il-13ra1 Protein, si:ch211-150g2.2 Protein, interleukin 13 receptor subunit alpha 2 Protein, interleukin 13 receptor subunit alpha 1 Protein, interleukin 13 receptor, alpha 1 Protein, interleukin 13 receptor, alpha 1-like Protein, IL13RA2 Protein, IL13RA1 Protein, Il13ra1 Protein, il13ra1 Protein, LOC100360218 Protein
- Background
- Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha, IL-13 R alpha ' or NR4, is now referred to as IL-13 R alpha 1. The high-affinity IL-13 binding protein, previously also designated IL-13 R or IL-13 R alpha ', is now referred to as IL-13 R alpha 2.
- Molecular Weight
- 37.59 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- XP_005594500
- Pathways
- JAK-STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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