IL-9 Protein (AA 19-144) (Fc Tag)
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- Target See all IL-9 (IL9) Proteins
- IL-9 (IL9) (Interleukin 9 (IL9))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 19-144
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL-9 protein is labelled with Fc Tag.
- Purpose
- Human IL-9 Protein
- Sequence
- Gln19-Ile144
- Characteristics
- Recombinant Human IL-9 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln19-Ile144.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human IL-9, hFc Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Anti-IL-9 Antibody, hFc Tag with the EC50 of 14.5ng/ml determined by ELISA. See testing image for detail.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- IL-9 (IL9) (Interleukin 9 (IL9))
- Alternative Name
- IL-9 (IL9 Products)
- Synonyms
- IL9 Protein, IL-9 Protein, Il-9 Protein, P40 Protein, HP40 Protein, interleukin 9 Protein, IL9 Protein, il9 Protein, Il9 Protein
- Background
- IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pleiotropic functions, IL-9 has been demonstrated to be involved in several diseases, such as cancer, autoimmunity and other pathogen-mediated immune-regulated diseases. In this review, we focus on the role of Th9 and IL-9-producing cells in allergic asthma.
- Molecular Weight
- 40.9 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.
- UniProt
- P15248
- Pathways
- JAK-STAT Signaling
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