IL-4 Protein (AA 25-153) (His tag)
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- Target See all IL-4 (IL4) Proteins
- IL-4 (IL4) (Interleukin 4 (IL4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 25-153
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Origin
- Cynomolgus
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL-4 protein is labelled with His tag.
- Purpose
- Cynomolgus IL-4 Protein
- Sequence
- His25-Ser153
- Characteristics
- Recombinant Cynomolgus IL-4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains His25-Ser153.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 13.48 nM as determined in SPR assay (Biacore T200). See testing image for detail.
- Top Product
- Discover our top product IL4 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- IL-4 (IL4) (Interleukin 4 (IL4))
- Alternative Name
- IL-4 (IL4 Products)
- Synonyms
- IL4 Protein, IL-4 Protein, BCGF-1 Protein, BCGF1 Protein, BSF-1 Protein, BSF1 Protein, Il-4 Protein, Il4e12 Protein, IL2 Protein, interleukin 4 Protein, IL4 Protein, Il4 Protein
- Background
- Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation.In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor. .
- Molecular Weight
- 16.03 kDa. Due to glycosylation, the protein migrates to 23-28 kDa based on Tris-Bis PAGE result.
- Pathways
- JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
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