IL-2 Protein (AA 21-153)
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- Target See all IL-2 (IL2) Proteins
- IL-2 (IL2) (Interleukin 2 (IL2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-153
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purpose
- Human IL-2 Protein
- Sequence
- Ala21-Thr153
- Characteristics
- Recombinant Human IL-2 Protein is expressed from E.coli without tag.It contains Ala21-Thr153.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 15.2nM as determined in SPR assay (Biacore T200). See testing image for detail.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in 100 mM Acetic Acid.
- Buffer
- Lyophilized from 0.22μm filtered solution in 100 mM Acetic Acid. Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- IL-2 (IL2) (Interleukin 2 (IL2))
- Alternative Name
- IL-2 (IL2 Products)
- Synonyms
- IL2 Protein, IL-2 Protein, il2 Protein, TCGF Protein, lymphokine Protein, Il-2 Protein, POIL2 Protein, interleukin 2 Protein, interleukin-15 Protein, IL2 Protein, il2 Protein, LOC100303688 Protein, Il2 Protein
- Background
- Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15,5 - 16 kDa protein that regulates the activities of white blood cells (leukocytes, often lymphocytes) that are responsible for immunity. IL-2 has essential roles in key functions of the immune system, tolerance and immunity, primarily via its direct effects on T cells.
- Molecular Weight
- The protein has a predicted 15.5 kDa same as Tris-Bis PAGE result.
- UniProt
- P60568
- Pathways
- JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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