IL1R2 Protein (His tag)
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- Target See all IL1R2 Proteins
- IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL1R2 protein is labelled with His tag.
- Sequence
- Phe14-Glu343
- Purity
- > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human IL-1R2, His Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Human IL-1 Beta, His Tag with the EC50 of 15.1ng/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product IL1R2 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
- Storage
- 4 °C,-80 °C
- Storage Comment
- Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))
- Alternative Name
- IL-1R2 (IL1R2 Products)
- Synonyms
- CD121b Protein, CDw121b Protein, IL-1R-2 Protein, IL-1RT-2 Protein, IL-1RT2 Protein, IL1R2c Protein, IL1RB Protein, Il1r-2 Protein, IL-1R2 Protein, interleukin 1 receptor type 2 Protein, interleukin 1 receptor, type II Protein, interleukin-like Protein, IL1R2 Protein, Il1r2 Protein, KK34 Protein
- Background
- IL-1R-2, IL-1RT-2, IL-1RT2, CDw121b, IL-1R-beta, CD121b, IL1RB, IL1R2, IL-1 RII, MGC47725,Interleukin (IL)-1 has been reported to be involved in the development of tuberculosis (TB). IL1R1 and IL1R2 encode a cytokine receptor that belongs to the IL-1 receptor family.IL1R2 (Interleukin 1 Receptor Type 2) is a Protein Coding gene. Diseases associated with IL1R2 include Endometriosis and Mastitis. Among its related pathways are Hematopoietic cell lineage and IL-1 signaling pathway. Gene Ontology (GO) annotations related to this gene include interleukin-1 receptor activity and interleukin-1, type II, blocking receptor activity.
- Molecular Weight
- 38.9 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- NP_004624
- Pathways
- NF-kappaB Signaling
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